Dicyclomine Used for Anxiety? Discover Benefits & Side Effects Explained

When it comes to managing anxiety, people often seek out various medications to help them cope. One drug that has come under discussion is dicyclomine. Primarily used for treating irritable bowel syndrome (IBS), there’s been curiosity about whether it can also help with anxiety. In this article, we’ll explore “Dicyclomine Used for Anxiety,” its benefits, and side effects. By the end, you’ll have a comprehensive understanding of whether this medication might be right for you or someone you know dealing with anxiety.

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What is Dicyclomine?

Dicyclomine, commonly known by its brand name Bentyl, is an anticholinergic medication used primarily to treat irritable bowel syndrome (IBS). It works by relaxing the muscles in the gut and relieving spasms. This relaxation helps reduce the symptoms associated with IBS, such as abdominal pain and cramping. Dicyclomine Used for Anxiety.

Dicyclomine Used for Anxiety
Dicyclomine Used for Anxiety

Is Dicyclomine Used for Anxiety?

The primary use of dicyclomine is not for anxiety; it is prescribed for IBS. However, due to its muscle-relaxing properties, there has been some interest in its potential off-label use for anxiety. Anxiety often involves muscle tension, and a medication that relaxes muscles might provide some relief. But is dicyclomine used for anxiety in a clinically approved manner? Not typically. Medical professionals generally prefer other medications specifically designed to treat anxiety.

Dicyclomine Used for Anxiety
Dicyclomine Used for Anxiety

How Does Dicyclomine Work?

Dicyclomine works by blocking the action of acetylcholine, a neurotransmitter that stimulates muscle contractions in the gut. By inhibiting acetylcholine, dicyclomine helps to relax the smooth muscles of the intestines, thereby reducing cramping and discomfort. This mechanism, while effective for IBS, is not directly targeted at anxiety relief.

Dicyclomine for Anxiety: An Overview

Historically, dicyclomine has not been a go-to medication for anxiety. Its primary design and FDA approval focus on gastrointestinal issues. However, some patients and doctors have explored its potential for anxiety relief, given that anxiety can exacerbate IBS symptoms and vice versa. Comparatively, dicyclomine for anxiety stands on shaky ground when placed alongside well-established anti-anxiety medications like SSRIs and benzodiazepines. Dicyclomine Used for Anxiety.

Benefits of Using Dicyclomine for Anxiety

The potential benefits of using dicyclomine for anxiety are mostly anecdotal. Some users have reported feeling calmer due to the muscle-relaxing effects, which can indirectly reduce anxiety symptoms. However, scientific studies are limited in this area, and the benefits are not universally acknowledged in the medical community. Dicyclomine used for anxiety might offer some short-term relief but lacks the targeted action of conventional anxiety medications.

Dicyclomine Used for Anxiety
Dicyclomine Used for Anxiety

Side Effects of Dicyclomine Used for Anxiety

Like all medications, dicyclomine comes with a range of side effects. Common side effects include:

  • Dry mouth
  • Dizziness
  • Blurred vision
  • Nausea
  • Light-headedness

Severe side effects, although rare, can include:

  • Confusion
  • Difficulty urinating
  • Severe constipation
  • Rapid or irregular heartbeat

These side effects highlight why dicyclomine used for anxiety might not be the best choice, especially given the availability of medications specifically designed to manage anxiety with a more favorable side effect profile. Dicyclomine Used for Anxiety.

Comparing Dicyclomine to Other Anxiety Medications

When comparing dicyclomine to other anxiety medications, it’s essential to consider both effectiveness and safety. Traditional anxiety medications like SSRIs (Selective Serotonin Reuptake Inhibitors) and benzodiazepines are well-researched and widely prescribed. They have a more predictable effect on anxiety symptoms and a side effect profile that is better understood in the context of long-term use for anxiety. Dicyclomine, on the other hand, is less predictable and not specifically designed for anxiety management.

Who Should Avoid Dicyclomine Used for Anxiety??

Dicyclomine is not suitable for everyone. People with the following conditions should avoid using it:

  • Glaucoma
  • Myasthenia gravis
  • Severe ulcerative colitis
  • Gastroesophageal reflux disease (GERD)
  • Before using, women who are nursing or pregnant should also speak with their doctor.

Given these contraindications, using dicyclomine for anxiety could pose additional risks to these populations. Dicyclomine Used for Anxiety.

Dicyclomine Used for Anxiety
Dicyclomine Used for Anxiety

How to Use Dicyclomine for Anxiety

If you and your healthcare provider decide that dicyclomine might be worth trying for anxiety, it’s important to follow the prescribed dosage and administration guidelines. Typically, dicyclomine is taken in doses ranging from 10 mg to 20 mg, up to four times daily. However, for anxiety, the dosage might be adjusted. Always follow your healthcare provider’s instructions to minimize risks and monitor for any adverse effects.

Dicyclomine Interaction with Other Medications

Dicyclomine can interact with several other medications, which can either diminish its effectiveness or increase the risk of side effects. Common interactions include:

  • Antacids
  • Anti-anxiety medications
  • Antihistamines
  • Monoamine oxidase inhibitors (MAOIs)

Managing these interactions is crucial if considering dicyclomine for anxiety. Always inform your healthcare provider of all the medications you are taking to avoid harmful interactions.

Patient Experiences with Dicyclomine for Anxiety

Real-life experiences with dicyclomine for anxiety are mixed. Some patients have reported a reduction in anxiety symptoms due to the muscle-relaxing effects, while others have found it ineffective or have experienced unwanted side effects. These varied experiences highlight the importance of personalized medical advice and cautious experimentation under a doctor’s supervision.

Expert Opinions on Dicyclomine for Anxiety

Medical professionals generally do not recommend dicyclomine as a first-line treatment for anxiety. Most experts prefer medications specifically designed for anxiety, given their targeted action and extensive research supporting their use. However, some might consider it in specific cases where patients have coexisting IBS and anxiety, and other treatments have failed.

Alternatives to Dicyclomine for Anxiety

There are several alternatives to dicyclomine for anxiety, Dicyclomine Used for Anxiety, including:

  • Serotonin and Norepinephrine Reuptake Inhibitors, or SNRIs,
  • Benzodiazepines
  • Beta-blockers
  • Cognitive-behavioral therapy (CBT)
  • Mindfulness and relaxation techniques

Each alternative has its benefits and potential side effects, and what works best will depend on the individual’s specific situation and medical history.


In summary, while dicyclomine is an effective medication for IBS, its use for anxiety is not well-supported by scientific evidence. The potential benefits are mostly anecdotal, and the risks of side effects and drug interactions are significant. If you are considering using dicyclomine for anxiety, it is crucial to consult with a healthcare provider to explore all your options and find the most appropriate treatment for your needs.


  1. WebMD
  2. Mayo Clinic
  3. Healthline


1. Can dicyclomine help with anxiety?

Dicyclomine is not typically prescribed for anxiety. While it may provide some muscle relaxation, there are more effective and better-researched medications available for treating anxiety.

2. What are the common side effects of dicyclomine?

Common side effects include dry mouth, dizziness, blurred vision, nausea, and light-headedness. Severe side effects can include confusion, difficulty urinating, and rapid or irregular heartbeat.

3. How should I take dicyclomine if prescribed for anxiety?

If your healthcare provider prescribes dicyclomine for anxiety, follow their dosage instructions carefully. Typically, it is taken 10-20 mg up to four times daily, but the dosage might vary.

4. Are there alternatives to dicyclomine for anxiety?

Yes, there are many alternatives, including SSRIs, SNRIs, benzodiazepines, beta-blockers, and non-pharmacological treatments like CBT and mindfulness techniques.

5. Who should avoid taking dicyclomine?

People with glaucoma, myasthenia gravis, severe ulcerative colitis, GERD, or those who are pregnant or breastfeeding should avoid dicyclomine unless advised otherwise by a healthcare provider.

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